HƯỚNG NGHIÊN CỨU

TIỀM LỰC

Nguyễn Thị Hoài

Giáo sư Tiến sĩ

Trần Hữu Dũng

Phó Giáo sư Tiến sĩ

Hồ Hoàng Nhân

Tiến sĩ

Lê Hoàng Hảo

Thạc sĩ

Lê Thị Loan Chi

Tiến sĩ

Trương Viết Thành

Tiến sĩ

Đào Thị Cẩm Minh

Tiến sĩ

Hồ Việt Đức

Phó Giáo sư Tiến sĩ

Nguyễn Viết Khẩn

Thạc sĩ

Võ Thị Hồng Phượng

Thạc sĩ

Ngô Thị Thu Hằng

Thạc sĩ

Trần Thái Sơn

Thạc sĩ

Lưu Ng Nguyệt Trâm

Thạc sĩ

Nguyễn Phước Bích Ngọc

Thạc sĩ

Nguyễn Hữu Tiến

Thạc sĩ

Lê Thị Bích Hiền

Thạc sĩ

Đoàn Thị Ái Nghĩa

Thạc sĩ

Trần Thị Thùy Linh

Thạc sĩ

Võ Quốc Hùng

Thạc sĩ

Phan Đặng Thục Anh

Thạc sĩ

Hoàng Xuân Huyền Trang

Thạc sĩ

Nguyễn Thị Như Ngọc

Thạc sĩ

Trần Thế Huân

Thạc sĩ

Lê Trọng Nhân

Thạc sĩ

Ngô Thị Kim Cúc

Thạc sĩ

Nguyễn Thị Quỳnh Như

Dược sĩ

Bùi Thị Thu Huyền

Dược sĩ

Đoàn Quốc Tuấn

Thạc sĩ

Nguyễn Khánh Thùy Linh

Thạc sĩ

CÔNG BỐ KHOA HỌC

1. Ho HN, Le HH, Le TG, et al. Formulation and characterization of hydroxyethyl cellulose-based gel containing metronidazole-loaded solid lipid nanoparticles for buccal mucosal drug delivery. International Journal of Biological Macromolecules. 2022;194:1010-1018. doi: 10.1016/j.ijbiomac.2021.11.161

2. Viet Cuong LC, Nhi NPK, Ha TP, et al. A new steroidal saponin from the aerial parts of Solanum torvum. Natural Product Research. 2021:1-6. doi: 10.1080/14786419.2021.1908282

3. Ho DV, Nguyen HT, Vu T, Pham TV, Nguyen HM. Antioxidant Activity of a New Xanthone Derivative from Aspidistra Letreae : In Vitro and In Silico Studies. Chemistry & Biodiversity. 2021;18(4). doi: 10.1002/cbdv.202001008

4. Tran T, Vo T, Vo T, Cao T, Tran T. Synthesis and Evaluation of the Acetylcholinesterase Inhibitory Activities of Some Flavonoids Derived from Naringenin. The Scientific World Journal. 2021;2021:1-10. doi: 10.1155/2021/4817900

5. Oanh VTK, Ha NTT, Duc HV, Thuc DN, Hang NTM, Thanh LN. New triterpene and nor-diterpene derivatives from the leaves of Adinandra poilanei. Phytochemistry Letters. 2021;46:110-113. doi: 10.1016/j.phytol.2021.10.003

6. Nguyen KV, Nguyen TOT, Ho DV, Heinämäki J, Raal A, Nguyen HT. In Vitro Acetylcholinesterase Inhibitory and Antioxidant Activity of Alphonsea tonkinensis ADC. Natural Product Communications. 2021;16(9):1934578X2110421. doi: 10.1177/1934578x211042134

7. Nguyen HM, Nguyen HT, Seephan S, et al. Antitumor activities of Aspiletrein A, a steroidal saponin from Aspidistra letreae, on non-small cell lung cancer cells. BMC Complementary Medicine and Therapies. 2021;21(1). doi: 10.1186/s12906-021-03262-w

8. Pham TV, Le TQ, Le AT, Vo HQ, Ho DV. Phytochemical Constituents of Annona reticulata and their Cytotoxic Activity. Letters in Organic Chemistry. 2020;17(3):206-210. doi: 10.2174/1570178616666190724123004

9. . . . . doi: 10.1016/j.jddst.2020.101801

10. Trong Le N, Viet Ho D, Quoc Doan T, et al. Biological Activities of Essential Oils from Leaves of Paramignya trimera (Oliv) Guillaum and Limnocitrus littoralis (Miq) Swingle. Antibiotics. 2020;9(4):207. doi: 10.3390/antibiotics9040207

11. Nguyen KV, Ho DV, Nguyen HM, et al. chiro-Inositol Derivatives from Chisocheton paniculatus Showing Inhibition of Nitric Oxide Production. Journal of Natural Products. 2020;83(4):1201-1206. doi: 10.1021/acs.jnatprod.9b01239

12. Trong Le N, Viet Ho D, Quoc Doan T, et al. In Vitro Antimicrobial Activity of Essential Oil Extracted from Leaves of Leoheo domatiophorus Chaowasku, DT Ngo and HT Le in Vietnam. Plants. 2020;9(4):453. doi: 10.3390/plants9040453

13. Ho DV, Hoang HNT, Vo HQ, et al. Three new steroidal saponins from Aspidistra letreae plants and their cytotoxic activities. Journal of Natural Medicines. 2020;74(3):591-598. doi: 10.1007/s11418-020-01395-9

14. Tran T, Le M, Tran T, Tran T, Thai K. Design of Curcumin and Flavonoid Derivatives with Acetylcholinesterase and Beta-Secretase Inhibitory Activities Using in Silico Approaches. Molecules. 2020;25(16):3644. doi: 10.3390/molecules25163644

15. Tran T, Le M, Nguyen T, Tran T, Tran T, Thai K. Synthesis, In Silico and In Vitro Evaluation for Acetylcholinesterase and BACE-1 Inhibitory Activity of Some N-Substituted-4-Phenothiazine-Chalcones. Molecules. 2020;25(17):3916. doi: 10.3390/molecules25173916

16. Hoang THX, Ho DV, Van Phan K, Le QV, Raal A, Nguyen HT. Effects of Hippeastrum reticulatum on memory, spatial learning and object recognition in a scopolamine-induced animal model of Alzheimer’s disease. Pharmaceutical Biology. 2020;58(1):1107-1113. doi: 10.1080/13880209.2020.1841810

17. Nguyen KV, Ho DV, Le NT, et al. Flavonoids and alkaloids from the rhizomes of Zephyranthes ajax Hort and their cytotoxicity. Scientific Reports. 2020;10(1). doi: 10.1038/s41598-020-78785-2

18. Tran T, Tran T, Tran T, et al. Synthesis, In Silico and In Vitro Evaluation of Some Flavone Derivatives for Acetylcholinesterase and BACE-1 Inhibitory Activity. Molecules. 2020;25(18):4064. doi: 10.3390/molecules25184064

19. Minh Nguyen H, Truong Nguyen H, Win N, et al. Antimelanogenic Activity of Ocotillol‐Type Saponins from Panax vietnamensis. Chemistry & Biodiversity. 2020;17(5). doi: 10.1002/cbdv.202000037

20. Le NT, Donadu MG, Ho DV, et al. Biological activities of essential oil extracted from leaves of Atalantia sessiflora Guillauminin Vietnam. The Journal of Infection in Developing Countries. 2020;14(09):1054-1064. doi: 10.3855/jidc.12469

21. Pham TV, Bach HKT, Ho DV, Nguyen BC. Chemical constituents from the Knema globularia fruits and their in vitro cytotoxicity. Natural Product Research. 2020;36(1):256-262. doi: 10.1080/14786419.2020.1777416

22. Ho HN, Le TG, Dao TTT, et al. Development of Itraconazole-Loaded Polymeric Nanoparticle Dermal Gel for Enhanced Antifungal Efficacy. Journal of Nanomaterials. 2020;2020:1-11. doi: 10.1155/2020/8894541

23. . In Vitro Cytotoxic Activity of Constituents of the Aerial Parts of Glycosmis parviflora. Tropical Journal of Natural Product Research. 2020;4(10):703-707. doi: 10.26538/tjnpr/v4i10.8

24. Yen PH, Cuc NT, Huong PTT, et al. Araliachinoside A: A New Triterpene Glycoside From Aralia chinensis Leaves. Natural Product Communications. 2020;15(9):1934578X2095275. doi: 10.1177/1934578X20952756

25. Tran L, Ho D, Le D, Nguyen H, Raal A. The effect of Pogostemon auricularius fractions and its compounds on some proinflammatory and anti-inflammatory molecules in LPS-stimulated RAW 2647 macrophages. American Journal of Physiology, Biochemistry and Pharmacology. 2020;10(1):1. doi: 10.5455/ajpbp.20190920041706

26. Viet Nguyen K, Laidmäe I, Kogermann K, et al. Preformulation Study of Electrospun Haemanthamine-Loaded Amphiphilic Nanofibers Intended for a Solid Template for Self-Assembled Liposomes. Pharmaceutics. 2019;11(10):499. doi: 10.3390/pharmaceutics11100499

27. Nguyen HT, Tran LTT, Ho DV, Phan KV, Raal A, Morita H. Three new inositol derivatives from Chisocheton paniculatus. Tetrahedron Letters. 2019;60(28):1841-1844. doi: 10.1016/j.tetlet.2019.06.015

28. Doan TQ, Ho DV, Trong Le N, et al. Chemical composition and anti-inflammatory activity of the essential oil from the leaves of Limnocitrus littoralis (Miq) Swingle from Vietnam. Natural Product Research. 2019;35(9):1550-1554. doi: 10.1080/14786419.2019.1652286

29. Ho DV, Tran LTT, Le DV, et al. A New Triterpene and a New Phloroglucinol Derivative from the Aerial Parts of Pogostemon auricularius. Chemistry of Natural Compounds. 2019;55(5):890-894. doi: 10.1007/s10600-019-02839-9

30. Tuan DQ, Duc HV, Nhan LT, Anh LT, Hoai NT, Raal A. Constituents of Essential Oils from the Leaves of Paramignya trimera (Oliv) Guillaum from Vietnam. Journal of Essential Oil Bearing Plants. 2019;22(2):391-395. doi: 10.1080/0972060X.2019.1582362

31. Tran LTT, Ho DV, Le DV, Van Phan K, Nguyen HT, Raal A. Apoptosis-Inducing Effect of Pogostemin A Isolated from the Aerial Parts ofPogostemon auriculariusAgainst the Human Lung Cancer Cells. Journal of Biologically Active Products from Nature. 2019;9(5):320-327. doi: 10.1080/22311866.2019.1687334

32. Chi LTL, Suharto A, Da HL, Chanthamath S, Shibatomi K, Iwasa S. Catalytic Asymmetric Intermolecular Cyclopropanation of a Ketone Carbene Precursor by a Ruthenium(II)-Pheox Complex. Advanced Synthesis & Catalysis. 2019;361(5):951-955. doi: 10.1002/adsc.201801077

33. Le CTL, Ozaki S, Chanthamath S, Shibatomi K, Iwasa S. Direct Catalytic Asymmetric Cyclopropylphosphonation Reactions of N,N-Dialkyl Groups of Aniline Derivatives by Ru(II)-Pheox Complex. Organic Letters. 2018;20(15):4490-4494. doi: 10.1021/acs.orglett.8b01788

34. Nguyen HT, Doan HT, Ho DV, Pham KT, Raal A, Morita H. Huperphlegmines A and B, two novel Lycopodium alkaloids with an unprecedented skeleton from Huperzia phlegmaria , and their acetylcholinesterase inhibitory activities. Fitoterapia. 2018;129:267-271. doi: 10.1016/j.fitote.2018.07.016

35. Dung TH, Huong LT, Yoo H. Morphological Feature of Pluronic F127 and Its Application in Burn Treatment. Journal of Nanoscience and Nanotechnology. 2018;18(2):829-832. doi: 10.1166/jnn.2018.14880

36. Nguyen HT, Tran LTT, Ho DV, Le DV, Raal A, Morita H. Pogostemins A-C, three new cytotoxic meroterpenoids from Pogostemon auricularius. Fitoterapia. 2018;130:100-104. doi: 10.1016/j.fitote.2018.08.015

37. Tran LTT, Ho DV, Le DV, Hung TM, Nguyen HT, Raal A. Three new phloroglucinol derivatives from the aerial parts of Pogostemon auricularius and their cytotoxic activity. Phytochemistry Letters. 2018;28:88-92. doi: 10.1016/j.phytol.2018.09.016

38. Nguyen HT, Ho DV, Nguyen PDQ, Vo HQ, Do TT, Raal A. Cytotoxic Evaluation of Compounds Isolated from the Aerial Parts of Hedyotis pilulifera and Methanol Extract of Inonotus obliquus. Natural Product Communications. 2018;13(8):1934578X1801300. doi: 10.1177/1934578X1801300805

39. Doan TH, Ho VD, Le TBH, et al. Two new abietane diterpenes huperphlegmarins A and B from Huperzia phlegmaria. Natural Product Research. 2018;33(14):2051-2059. doi: 10.1080/14786419.2018.1484462

40. Ho DV, Vo HQ, Nguyen TH, Do TT, Nguyen HT. A New Cytotoxic Tetrahydroxanthene-1,3(2H)-dione Derivative from Uvaria cordata and Structure Revision of Valderramenol A. Natural Product Communications. 2018;13(5):1934578X1801300. doi: 10.1177/1934578X1801300517

41. Hoai NT, Duc HV, Raal A, Morita H. A New Limonoid from Chisocheton paniculatus Fruit Collected in Vietnam and Its NO Production Inhibitory Activity. Natural Product Communications. 2018;13(10):1934578X1801301. doi: 10.1177/1934578X1801301005

42. Nguyen HT, Ho DV, Vo HQ, et al. Antibacterial activities of chemical constituents from the aerial parts of Hedyotis pilulifera. Pharmaceutical Biology. 2017;55(1):787-791. doi: 10.1080/13880209.2017.1279673

43. Ho VD, Hoang TNH, Vo QH, et al. Cycloartane-type triterpene glycosides anopanins A-C with monoacyldigalactosylglycerols from Anodendron paniculatum. Phytochemistry. 2017;144:113-118. doi: 10.1016/j.phytochem.2017.09.004

44. Ho HN, Laidmäe I, Kogermann K, et al. Development of electrosprayed artesunate-loaded core–shell nanoparticles. Drug Development and Industrial Pharmacy. 2017;43(7):1134-1142. doi: 10.1080/03639045.2017.1300163

45. Sak K, Nguyen TH, Ho VD, Do TT, Raal A. Cytotoxic effect of chamomile (Matricaria recutita) and marigold (Calendula officinalis) extracts on human melanoma SK-MEL-2 and epidermoid carcinoma KB cells. Cogent Medicine. 2017;4(1):1333218. doi: 10.1080/2331205X.2017.1333218

46. Dung TH, Do LT, Loan TT, Yoo H. Preparation and Biophysical Characterization of Poly(amidoamine) Dendrimer-Poly(acrylic acid) Graft. Journal of Nanoscience and Nanotechnology. 2015;15(1):684-687. doi: 10.1166/jnn.2015.8378

47. Ho DV, Kodama T, Le HTB, et al. A new polyoxygenated cyclohexene and a new megastigmane glycoside from Uvaria grandiflora. Bioorganic & Medicinal Chemistry Letters. 2015;25(16):3246-3250. doi: 10.1016/j.bmcl.2015.05.066

48. Raal A, Hoai N, Duc H, Thao D, Orav A. Selectivity of Pinus sylvestris extract and essential oil to estrogen-insensitive breast cancer cells Pinus sylvestris against cancer cells. Pharmacognosy Magazine. 2015;11(44):290. doi: 10.4103/0973-1296.166052

49. Ho HN, Tran TH, Tran TB, Yong CS, Nguyen CN. Optimization and Characterization of Artesunate-Loaded Chitosan-Decorated Poly(D,L-lactide-co-glycolide) Acid Nanoparticles. Journal of Nanomaterials. 2015;2015:1-12. doi: 10.1155/2015/674175

50. Nhiem NX, Van Kiem P, Van Minh C, et al. Anti-influenza Sesquiterpene from the Roots of Reynoutria japonica. Natural Product Communications. 2014;9(3):1934578X1400900. doi: 10.1177/1934578X1400900308

51. Cuong NM, Khanh PN, Duc HV, et al. Vasorelaxing Activity of Two Coumarins from <i>Murraya paniculata</i> Leaves. Biological and Pharmaceutical Bulletin. 2014;37(4):694-697. doi: 10.1248/bpb.b13-00905

52. Cuong NM, Khanh PN, Huyen PT, et al. Vascular L-Type Ca2+Channel Blocking Activity of Sulfur-Containing Indole Alkaloids fromGlycosmis petelotii. Journal of Natural Products. 2014;77(7):1586-1593. doi: 10.1021/np500076v

53. Tung MHT. Cytotoxic Compounds from Brucea mollis. Scientia Pharmaceutica. 2013;81(3):819-831. doi: 10.3797/scipharm.1206-02